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Milk thistle and its derivative compounds: a review of opportunities for treatment of liver disease

Finally, prospects for ferroptosis-based interventions and future directions point to several promising treatment avenues, including regulating iron homeostasis via chelators or TfR1/FPN modulation, using antioxidants and lipid peroxidation inhibitors to target GPX4 and ACSL4, or employing gene therapies and stem cell/exosome approaches to combat ferroptosis

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It also lowered free radical levels and protected mitochondria from amyloid-induced dysfunction [29]