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Genetic nicotinamide N-methyltransferase (Nnmt) deficiency in male mice improves insulin sensitivity in diet-induced obesity but does not affect glucose tolerance

Heffernan 2001a Mouse studies using chronic osmotic pump delivery showed AOD-9604 increased fat oxidation and plasma glycerol (a lipolysis marker) to a degree comparable with full-length hGH, without inducing hyperglycaemia or reducing insulin secretion

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