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In addition, orlistat's potential to cause liver damage and its association with severe liver outcomes, such as gallstone formation, obstructive jaundice, and acute liver failure, have been documented [68, 70]

The clinical efficacy of ALC and NAC has been evaluated in several trials [167, 172, 176, 199, 210, 237], the preliminary encouraging data and physiopathological frameworks support the need to study these compounds in this context and clarify their role [23, 24, 28, 199]

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