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Concurrently, lipid metabolism disorders can lead to impaired neuronal function, lysosomal dysfunction, and autophagic deficits, promoting neuronal death and contributing to various neurological diseases [83]

The liver and small intestines were taken from the rats

Typically, firms are expected to submit a written response within 15 business days of receipt of a Form 483 or Warning Letter, outlining corrections, preventive actions, and timelines

Ainsworth EA, Gillespie KM