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HFD inhibits the transcription of key antioxidant genes by triggering NRF2 translocation into obese mouse Tregs nucleus, causing a rapid decline in HO-1 expression in Tregs, leading to enhanced oxidative stress and possible ferroptosis, and causing an intensification of obesity and inflammatory responses (156) ( Figure 3 )
Back to Work IV Drip Had an exhausting weekend, recovered from a severe cold, or pushed yourself through an intense gym session
PLoS ONE 7 , e34169 (2012)
