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The cytoprotective effect of BPC 157 against colonic ischemia/reperfusion-mediated mucosal damage is associated with the activation of the collateral circulation, which circumvents obstructed sites and results in the resolution of the obstruction, reduction of oxidative stress and normalization of NO synthesis

The therapeutic effects encompassed improvements in both soft and hard tissues

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the efficiency, quality, and translatability differ between identified ME/CFS biomarkers, with limited reproducibility of findings between studies [23, 61]