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Platelets play a critical role in endometriosis-associated fibrogenesis: activated platelets within lesions release numerous growth factors, cytokines, and chemokines such as TGF-1, platelet-derived growth factor (PDGF), epidermal growth factor (EGF), and connective tissue growth factor (CTGF)

This posits that even though Fragment 176-191 may not directly activate beta-3 adrenergic receptors, the increased number of receptors might amplify the natural lipolytic response to endogenous catecholamines (like adrenaline), which are suggested to engage these receptors directly

Evaluation of MS related central fatigue using MR neuroimaging methods: Scoping review

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