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The diagnosis of vitamin B12 deficiency typically relies on low total B12 levels and elevated concentrations of homocysteine (Hcy), as well as levels of transcobalamin-bound B12 (holoTC) and methylmalonic acid (MMA), which serve as functional indicators of cobalamin insufficiency (Carmel and Sarrai, 2006)

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While its found in foods like meat and dairy, some individuals may struggle to absorb enough B12 through diet alone , leading to fatigue, memory issues, and other symptoms