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Head and Neck 45(3):547-554, 2023

The results of several large randomized controlled trials indicated that maintaining blood glucose at near normal concentrations was the most important step in limiting the risk of diabetic neuropathy and lower extremity amputation (70-72)

First, autophagy plays a protective role by inhibiting oxidative damage and apoptosis in CuSO 4 -induced testicular injury and spermatogenesis disruption, and second, autophagy plays an adverse role by promoting ferroptosis, thus aggravating the toxicity caused by CuSO 4 [100]