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Description
In HCC cell lines, upon sorafenib administration, p62 inhibited Nrf2 degradation and enhanced its nuclear accumulation
Rat livers were placed in Thermo-ROS solution containing 10% dimethyl sulfoxide (DMSO), and stored at -20 0 C for three days (72 hours)
Nevertheless, translating computationally predicted therapies into practice remains limited by difficulties in establishing causality, highlighting the need for more robust datasets linking dysbiosis to cutaneous pathogenesis and for direct functional validation
Eriksson CJ
