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Increased Glutathione Biosynthesis by Nrf2 Activation in Astrocytes Prevents p75NTRDependent Motor Neuron Apoptosis. Journal of Neurochemistry 97: 687696

Emerging innovations include stimuli-responsive delivery systems that release STING agonists in response to TME characteristics (acidic pH, hypoxia, ROS, specific enzymes), enabling precise spatiotemporal control of immune activation (163, 164)

doi: 10.1186/s12933-023-01983-5 49 IbarraN.PollittA.InsallR

354 BBB dysfunction The BBB is formed by components such as endothelial cells, astrocytes, and pericytes, along with the basement membrane, and together with other cells like microglia and neurons, they constitute the neurovascular unit (NVU)
