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Description
Studies have observed decreased cyclooxygenase-2 (COX-2) gene expression, reduced myeloperoxidase activity, and lower levels of pro-inflammatory cytokines including interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-)

This creates additional uncertainty when evaluating both safety and clinical outcomes

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doi: 10.1186/s12917-019-2227-8
