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mTOR (mechanistic target of rapamycin) suppresses autophagy under nutrient-rich conditions, and its inhibition via AMPK (adenosine monophosphate-activated protein kinase) is required for autophagy activation
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However, the compounds in TGP has low bioavailability and are easy to accumulate in the gastrointestinal tract (Fei et al., 2016)
The interplay of glucagon-like peptide-1 receptor trafficking and signalling in pancreatic beta cells
