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Br J Pharmacol 174(18):30323044 Guo K, van den Beucken T (2024) Advances in drug-induced liver injury research: in vitro models, mechanisms, omics and gene modulation techniques
Thus, ferroptosis induction may be one mechanism by which periodontitis increases the severity of T2DM
Compared with T2DM patients with healthy periodontal conditions, T2DM patients with periodontitis exhibit significantly higher expression of ferroptosis-related genes, such as IL-1, IL-6, NFE2L2, and ALOX5, in pancreatic tissue [158]
