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The primary preclinical evidence comes from mouse studies showing reduced body weight and adipose mass in diet-induced obese mice (2018), improved grip strength in aged mice (2024), and beneficial microbiome changes when combined with caloric restriction (2022)

For longer-term storage, keep it at 20C, which allows storage for several years without affecting the compounds structure or purity

Based on the encouraging clinical response seen with daratumumab-Kd in EQUULEUS [74], a phase III study (CANDOR) was conducted to further evaluate daratumumab-Kd in RRMM patients who had received 13 prior therapy lines [75]