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They are inconsistent with the hypothesis that LYSET has no impact on GNPT cleavage, as suggested by the trafficking model, but they do support the notion that LYSET serves as an anchor to maintain GNPT at the Golgi, regardless of cleavage

Its pathophysiology involves several mechanisms: Persistent hyperglycemia, along with toxic substrates, affects multiple cells in the peripheral nervous system, including Schwann cells, axons, and neurons in the dorsal root ganglion, as well as vascular cells

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Bilberry is rich in anthocyanins , which are plant pigments that exert a variety of beneficial effects in the human body, including functioning as antioxidants and modulating inflammatory processes (Tsuda 2012