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Most common causes of the discolouration include: Medications amino-salicyclic acid derivatives mesalazine/paraaminosalycylic acid/sulfasalazine doxorubicin , hydroxocobalamin , ibuprofen, phenothiazines, phenolphthalein, propofol , rifampicin/rifampin Dietary ingestants beeturia , rhubarb, blackberries, food dyes Metabolic abnormalities porphyria , urate crystals Hydroxocobalamin Early features of cyanide poisoning include nausea, vomiting, headache, dyspnoea, tachypnoea, hypertension, tachycardia, collapse and seizures

While the condition is the major cause of poor vitamin B 12 status in the elderly population, it is usually associated with atrophic gastritis, a chronic inflammation of the lining of the stomach that ultimately results in the loss of glands in the stomach (atrophy) and decreased stomach acid production (see Atrophic gastritis)

Biotin-GHK in hair follicle and hair loss: Scientific presentation

doi: 10.1056/NEJM199001113220205