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MTs in high-fat diet and obesity Based on epidemiological evidence, it can be concluded that ingestion of a diet high in fat is linked to the development of obesity

Funding Authors were supported by VALERE: Vanvitelli per la Ricerca Program, MIUR20152TE5PK, EPICHEMBIO CM1406, the Campania Regional Government Lotta alle Patologie Oncologiche iCURE (CUP B21c17000030007), Campania Regional Government FASE 2:IDEAL (CUP B63D18000560007), MIUR Proof of Concept (POC01_00043), Vanvitelli per la Ricerca Program AdipCare (ID 263)
When activated by stress or infection, NF-B translocates into the cell nucleus and triggers the expression of genes responsible for producing pro-inflammatory cytokines

Its cell cycle interference spans multiple phases: in ovarian cancer SKOV-3 cells, it downregulates cyclin B1 and CDK1key drivers of G2/M progressionthereby blocking the G0/G1-to-G2/M transition and inducing apoptosis (Ren et al., 2015
