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The kinetic description of the biorecognition process between p28 and the p53 family of proteins was completed by determining the association rate constant, k on

In addition, SOD proteins have the ability to bind to cell surface proteoglycans and extracellular matrix components in a positively-charged C-terminal region (extracellular matrix binding region)

The intervention group showed significantly lower severe hematologic toxicities (5% vs 23%, p = 0.03) and improved treatment completion rates compared to the placebo group

This suggests that lactate accumulation in severely degenerated discs may further impair cell function