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Some superoxides are transported to the cytosol, where they are dismutated to H 2 O 2 by the cytosolic enzyme SOD1 [16]

Cecil KM, DelBello MP, Morey R, Strakowski SM

In consequence, this stimulation enhanced intestinal permeability and alleviated inflammatory factors such as endotoxin, IL-1, and TNF present in the blood (Wu T.-R

[7] [87] In addition, bacteria in the distal portion of the small intestine and in the large intestine synthesize modest amounts of folate, and there are RFC receptors in the large intestine, so this in situ source may contribute to toward the cellular nutrition and health of the local colonocytes