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In addition, lower levels of tumor necrosis factor- (TNF-) and CGRP in the serum of patients enrolled in the CoQ10-arm, suggest that these effects are through the reduction of inflammatory processes (163)

Yet, de novo choline synthesis in humans is not sufficient to meet their metabolic needs such that healthy humans fed choline-deficient diets develop fatty liver, liver damage, and/or muscle damage (see Deficiency)

J Biol Regulat Homeostat Agents 38(6):45674582 Llavanera M, Delgado-Bermudez A, Ribas-Maynou J, Salas-Huetos A, Yeste M (2022) A systematic review identifying fertility biomarkers in semen: a clinical approach through omics to diagnose male infertility