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In regions of high metabolic activity, such as in the brain, oxidative stress is more likely due to the increased production of free radicals, namely the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS)

With the improvement of disease awareness and the progress of diagnostic technology, more CD patients have been diagnosed, which may also explain the increase in incidence and prevalence

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As the body's primary G-actin sequestering peptide, it maintains pools of monomeric actin available for rapid cytoskeletal reorganization, accelerating cell migration from distant sites to the wound