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Von Formaldehyde as a probe of DNA structure 4 mechanism of the initial reacition of formaldehyde with DNA
In this regard, a key mode of action to explain this relationship is via glucose transporter type 1 (GLUT1) which increases uptake of the oxidized form of ascorbic acid, dehydroascorbate and subsequently depletes glutathione (Yun et al., 2015)
Note that 9 mg and 12 mg are now the Phase-3-validated doses, while 1 mg, 4 mg, and 8 mg remain Phase 2 / research reference points
42 (3), BSR20212171
