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According to literature, gut microbiota modulation might lead to a decline in fat storage in adipocytes due to incrementing fasting-induced adipose factor (FIAF) levels, a suppressor of lipoprotein lipase (LPL) (30), and foster lipid oxidation in the liver and muscles via amplified activity of adenosine monophosphate-activated protein kinase (AMPK) (30)

The take-away : Rhodiola appears to be a better option for those with milder cases of depression, especially those who also struggle with fatigue or anxiety

High dietary fiber intake modulates the gut microbiota composition, suppressing microbial enzymes like TMA lyases, which are responsible for converting dietary choline and carnitine into TMA, the precursor to TMAO

Curr Opin Clin Nutr Metab Care 2012;15(6):597-604