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Nature 386 , 292296 (1997)

However, some possible reasons include: Condition known as tear-trough deformity Aging Skin dehydration Loss of bone structure due to age or trauma Insomnia Genetics Weight fluctuations Hyperpigmentation Overdevelopment of the muscle in the lower eyelid known as Orbicularis Oculi Hypertrophy Dark vascular veins below the eye Whatever the root cause is, Eyelight restylane filler can reverse the appearance of dark, hollow, or aging eyes

Oligonucleotides used for qPCR and their sequences are shown in Supplementary Table S7

this has created an important role for microbial lipases in food, pharmaceutical, papermaking, detergent, and biodiesel production, among other fields
