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[8] B12-deficient patients at risk for Lebers optic atrophy from chronic cyanide intake (e.g., smoking) should not be given cyanocobalamin due to the risk of irreversible neurological damage

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The mean dried blood spot MMA concentration quantified from 160 newborns was 16.8pmol/L (95th CI:15.917.6pmol/L per 8mmspot), with 95% reference intervals (2.5th to 97.5th percentile) for MMA of 9.89 to 29.3pmol/8mm blood spot (0.450 to 1.33mol/L whole blood)

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