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Overall, taken together with previous efforts, these insights encouragingly designate FOXO4-TP53 as a noteworthy complex not only for drug discovery studies combatting age-related diseases but also for our understanding of interactions of transcription factors

Abstract The methylenetetrahydrofolic acid reductase (MTHFR) C677T polymorphism causes an amino-acid change from alanine to valine and results in the enzyme becoming thermolabile and half decreased activity

Soares-Silva, M., Diniz, F

It has been shown that treatment with Bezafibrate could also reduce serum ALP value in patients with PSC [273] (NCT04309773)
