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Nat Rev Neurosci 12(6):359366 Paviour DC, Surtees RA, Lees AJ (2004) Diagnostic considerations in juvenile parkinsonism

Compared with those in the WT group, the expression levels of these five genes were lower in the control group ( P = 0.1413, 0.0098, 0.0006, 0.0007, and 0.3512 for Glp1r , Htr4 , Ntsr1 , Nos1 , and Ntrk1 , respectively), whereas the expression levels were significantly greater in the combination group than in the control group ( P = 0.0013, 0.0017, 0.0043, 0.0023, and 0.0016 for Glp1r , Htr4 , Ntsr1 , Nos1 , and Ntrk1 , respectively) (Fig

Parents are usually carriers, and may not have any symptoms

A final concentration of ~15 M adduct was used for the measurements