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Improving GPs awareness of menstrual wellbeing and when to consider endometriosis is vital but needs to recognise the complexity of the process and the decisions being made

'cause none of us are doing any of those things

In fact, oxidative stress can lead to the decrease of DNA-binding activities of activator protein-1 and CREB (cyclic AMP-response element-binding protein) which is associated with the reduction of BDNF (brain-derived neurotrophic factor) gene expression, as well as oxidative stress, and can result in impairment of NMDA channel function that is related to the decrease in BDNF gene expression

Shi et al., 2015