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This mechanistic insight provides a new biological framework for understanding the cardiorenal benefits of SGLT2 inhibitors and supports the development of ferroptosis-oriented therapeutic strategies for DKD

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A high prevalence of low serum / plasma B12 has also been reported among pregnant women (27.5% in 11 cohorts) and children (12.5% in 14 cohorts) (Smith et al., 2018)