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In this review, we principally focused on the potential effect of the herbal plants and their phytochemicals involved in modulating drug-induced nephrotoxicity.

Using an untargeted NMR-based metabolomics approach combined with multivariate and statistical analyses, we identified significant metabolic alterations and assessed their diagnostic potential

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Early detection is key, using: Serum ceruloplasmin levels 24-hour urinary copper excretion Liver biopsy or genetic testing If caught early, treatment with chelating agents like penicillamine can prevent long-term damage and give patients a near-normal life