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Evidence ranges from early laboratory work to clinical trials depending on the use the sections below cover the actual data and sources

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This combined approach results in improved glycemic control and significant weight reduction

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Preclinical evidence Mice with a deletion of the 22q11.2 locus containing most proteins expressed in mitochondria [19] show increased cytoplasmic 8-oxo-2-deoxyguanosine (suggesting mitochondrial DNA oxidation), reduced number of PV-immunoreactive interneurons, and weakened PNN in anterior cingulate cortex [15]

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10.1039/D1FO03746C

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