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Description
Strange et al., 2000)
Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin
The downside of skin whitening injections is that it is not convenient to be administered in addition to the fact that it is almost impossible to be provided in some countries
Additionally, several studies have documented paradoxical activation of MAPK pathway during preclinical testing or clinical trials of BRAF inhibitors in pLGGs (63, 64)
