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NMP was performed on nine human donor livers declined for transplantation: three were perfused without NAC (no-NAC group), and six organs perfused with an initial NAC bolus, followed by continuous infusion (NAC group), with hourly methaemoglobin perfusate measurements

Specifically, ferulic acid, a phenolic compound, has been shown to improve the gut microbiota dysbiosis induced by a high-fat diet, increase the accumulation of SCFA-producing bacteria in the gut and their receptor expression, reduce the levels of endotoxin-producing bacteria and serum endotoxins, and strengthen intestinal barrier function by inhibiting the colonic TLR4/NF-B inflammatory pathway [165]

doi: 10.4103/1673-5374.205108 65

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