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Cognitive enhancers are usually tested in this model but other treatments could also be considered

This reagent reacts with the thiol groups of GSH which convert 2-nitro-5-thiobenzoate (NTB ) to NTB 2 , thereby producing a yellow color, which can subsequently be quantified ( Glutathione Peroxidase GPx is measured by adding glutathione reductase (GR) to the sample after which nicotinamide adenine dinucleotide phosphate (NADPH) is transformed to a reduced state, allowing a decrease in absorbance to be subsequently measured (32)

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It contains the nitro (-NO 2 ) group, reduction takes place in this group and it is converted into the amino (-NH 2 ) group and the remaining structure is the same