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In the open-field test, line crossings and rearing behaviors were restored significantly in the 100 mg/kg group, indicating improved exploratory activity

When glutamate was injected into the ganglia innervating the temporalis or masseter muscle, there was a significant increase in nociception (decrease in afferent mechanical thresholds) that was attenuated by NMDAR antagonists (2R)-amino-5-phosphonovaleric acid, AP-V) or worsened by EAAT blockers (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid, TFB- TBOA) [267]

(Jul de 2000)
