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Diagnosis and treatment Diagnosing depression involves a thorough evaluation by a healthcare professional, which typically includes a clinical interview, standardized screening tools, and an assessment of the patients medical and psychological history
Either the overproduction of the Fe 2+ that is involved in the formation of lipid hydroperoxides through the Fenton reaction 111 or the inactivation of glutathione peroxidase 4, which is programmed to degrade lipid hydroperoxides, leads to intracellular lipid hydroperoxide accumulation to a lethal level, ultimately triggering ferroptosis 112

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