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[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Minotti G, Aust SD
(2) glutathione depletion disrupts redox balance
Superoxide radical can be generated by specialized enzymes, such as the xanthine or NADPH oxidases, or as a by-product of cellular metabolism, particularly the mitochondrial electron transport chain, and are converted to hydrogen peroxide by the superoxide dismutase (SOD)
MM, multiple myeloma
