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administration in the BALB/c hippocampi may be associated with the mechanisms of peptides nootropic and anxiolytic activities manifested specifically in this mouse strain

The occurrence of IVDD results from the combined effects of genetic and environmental factors

While selectivity over classical ERs is reported at relevant concentrations, nuclear-receptor cross-reactivity and downstream network effects remain theoretical risks in longer or higher-exposure studies

This finding not only supports KPV's candidacy as a research compound for IBD investigation but also unveils a paradigm for drug delivery, exploiting alterations in protein expression to enhance drug localization and activity