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Research indicates that low maternal B12 status is associated with a higher risk of adverse outcomes, including neural tube defects, preterm birth, low birth weight and potential impacts on cognitive development, although evidence of direct causation remains limited

The phenolic hydroxyl group contributes additional hydrogen bonding capacity, while the aliphatic chain increases hydrophobic character relative to shorter peptide analogues

Advances in pharmacological treatments, gene therapy, and neuromodulation techniques show great promise in restoring ENS function and improving clinical outcomes

This paper demonstrates that GABA and GAD67 act beyond their classic roles in inhibitory transmission and regulate activity-dependent morphogenesis of GABAergic axons and synapses in the adolescent neocortex