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For ferroptosis inducers combined with immune checkpoint inhibitors, sequential administration may maximize efficacy: initial ferroptosis induction promotes immunogenic cell death and antigen release, followed by checkpoint blockade to enhance T-cell activation and memory formation (236)

Zager, D.B., Wehmeyer, M.L., and Simpson, R.L., Educating Students with Autism Spectrum Disorders: Research-Based Principles and Practices , Routledge, 2012

Thyroid hormone receptor- agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways
In particularly, ACSL4 plays a crucial role in regulating ferroptosis, and its overexpression boosts the synthesis of -pufa6 PUFA and encourages ferroptosis (51)
