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The treated mice showed several other improvements

The signs and symptoms of vitamin B12 deficiency may include: fatigue difficulty thinking and remembering infertility heart palpitations pale skin dementia weight loss numbness and tingling in the hands and feet mood changes constipation a sore tongue low appetite Many people are unclear about precisely what these vitamins do despite vitamin B12 being so important for the bodys healthy function

Much of the current evidence is preclinical (cell and animal studies), and human data is still limited

B12 supplementation is extremely safe with no established upper limit for toxicity
