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Aging Cell 23 , e14161 (2024)
Its efficacy and tolerability is currently being evaluated in a phase 3 trial [77] (Table 2 )
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348 Similarly, in human chondrocytes stimulated by TNF, GLP-1 analogs (such as liraglutide) showed an anti-catabolic effect, reducing the mRNA expression of MMP-3, MMP-13, and ADAMTS5
