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Others bind receptors on Leydig cells and modify steroidogenesis, affecting testosterone synthesis

Recent experimental studies revealed that folate may improve endothelial function 98 by an enhancement of binding affinity of BH 4 to NOS by a pteridine-binding domain serving as a locus through which the active form 5-methyl tetrahydrofolate facilitates the electron transfer by BH 4 from the NOS reductase domain to heme

doi: 10.1046/j.1464-410x.1998.00683.x, 188
Mol Microbiol 96, 6883