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And we need human studies as well

Citrulline plays a crucial role in the urea cycle and serves as a precursor to L-arginine, which is subsequently converted into nitric oxide (NO), a key vasodilator involved in maintaining vascular tone, endothelial function, and blood pressure regulation [8]

Acupoint catgut embedding relieves colonic inflammatory injury by down-regulating NLRP3/Caspase-1 signaling pathway in rats with ulcerative colitis

These products are not manufactured under FDA-regulated conditions, may contain inconsistent concentrations of toxin, and have caused serious neurological injury in documented cases