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J hypertension (1997) 15(10):115965

PMC Gene Modulation: Up-regulates ~400 pro-repair genes while silencing ~200 pro-inflammatory or pro-fibrotic genes

Although three representative mutations identified in the three largest pedigrees of 5-reductase-2 deficiency are described above, there are documented mutations in all five exons of the gene, ranging from a single point defect to a deletion of the entire gene as noted in Figure 1(1, 4, 5)
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