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Furthermore, all rescue experiments in this study used chemical inhibitors or agonists, which may have the risk of off-target effects

Hammers et al[65] found an age-related reduction in the expression of IGF-I and individual IGF-I Ea and Eb splice variants as well as IGF-I receptor signaling, following injury

[3] Oxidative stress reduction Oxidative stress markers, including measured reactive oxygen species and lipid peroxidation products, fall by 35% with LipoEdge Glutathione supplementation, reflecting the direct intracellular antioxidant activity made possible by efficient cytosolic delivery

Nanoscale 7 , 2005520062 (2015)