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Originally discovered in human plasma in the 1970s, GHK-Cu is recognized for its roles in wound healing, collagen synthesis, and tissue repair
Besides, they can serve as a tight junction (TJ) modulator to trigger an intracellular signaling cascade, causing TJ disruption and actin cytoskeleton reorganization to form an intercellular "green channel" to help them to cross the blood-brain barrier (BBB) silently
Revista MedicoChirurgicala a Societatii de Medici Si Naturalisti Din Iasi July/September 2008;112(3):6415
