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doi: 10.1038/s41398-020-01125-5

Engineered biomimetic nanoparticles achieve targeted delivery and efficient metabolism-based synergistic therapy against glioblastoma

This diet was introduced as an anticonvulsant treatment for drug-refractory epilepsy, and has very low carbohydrate content as a means to induce a metabolic state similar to fasting but without caloric restriction

Prevention of oxidative stress buildup upon ETC shutdown is due to the increased prevalence of NADH, which in the presence of NADP+ and nicotinamide nucleotide transhydrogenase can form NADPH for reducing equivalents in oxidative stress repair reactions (Garcia et al., 2010
