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[DOI] [PubMed] [Google Scholar] 50.Lu Y., Zhang L., Wang C., Gong C

Binding of colipase reverses this inhibition either by attaching first to the interface and serving as an anchor for the binding of the lipase or by first forming a colipase-pancreatic-lipase complex that then binds to the lipid interface

The alternate arrangement of the R-domain in the 7MPE model is physically plausible as it places a cluster of electronegative side chains where our model has placed phosphates

In states of chronic GI inflammation, this mucus layer is often degraded, leaving the enterocytes exposed to harsh digestive enzymes and pathogenic bacteria